Herpes simplex virus

Replication of herpes simplex virus (HSV) in appropriate cell lines induces a marked cytopathy. This property is used in our assays (plaque or cytopathic effects inhibition) to evaluate and profile the activity of new antivirals against the propagation of HSV in cell culture. Our standard assays are performed using a HSV1 strain while HSV1 and 2 clinical isolates are available for compound profiling.