Respiratory Viruses

Our assays have been designed to expedite the discovery and development of new antivirals active against influenza, Respiratory Syncytial Virus (RSV) or Parainfluenza Virus (PIV) 3.

Influenza, RSV, PIV3 viruses platform
   - Screening and dose-response (CPE assay)
   - Plaque reduction assay
   - Profiling of drug activity against clinical isolates
   - Drug combination study
   - Generation of mutants by site-directed mutagenesis
   - Resistance generation in cell culture
   - Reverse genetics
   - Time of addition experiment
   - vRNA transcription/replication assay
   - Fusion assay